1. After digesting a meal the elevated blood glucose provides a signal to the pancreas to produce insulin.
2. Insulin is secreted by the pancreas into the bloodstream and circulates around the body.
3 & 4. Insulin binds to the receptor and activates 2nd messengers which increase absorption of glucose and its conversion to long-term energy stores (glycogen or fat).
5. The resultant lowering of blood glucose acts as a shut-off signal to the pancreas, preventing further production and release of insulin until blood glucose rises again.
6. There is no linkage in this state between the glucose-insulin system and androgen production and regulation.